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In the 3-way, double-blind, triple-dummy crossover trial, which included 210 patients with asthma, tiotropium bromide was shown to be of equal efficacy to the long-acting β-agnonist (LABA) salmeterol as a step-up therapy.Thus, tiotropium bromide represents an important alternative treatment for adults with poorly controlled, chronic asthma.Some of the current topics American Lung Association funded researchers are investigating include understanding the immune system’s role in asthma, the effect of mold on severe asthma; improving treatment of severe asthma in children, and studying genes and their role in controlling the immune response.
The CDC further found that only 34.2% of persons with asthma reported that they had been given a written action plan by their health–care providers, and 68.1% of persons with asthma said they had been educated on the proper steps to take during an asthma attack.
There have been advances in the diagnostic evaluation of patients suspected of having asthma.
The American Lung Association is committed to funding asthma research.
Our Awards and Grants Program funds top-notch researchers at important career crossroads to gain long-term commitment to lung health and disease research.
Asthma is a clinical syndrome that typically consists of increased airway hyperresponsiveness and recurrent episodes of airway obstruction and inflammation with subsequent remodeling.
As one of the most common conditions seen in the primary care setting, asthma is of great interest to the US Centers for Disease Control and Prevention (CDC).The normal range of Fe NO is 0 to 20 parts per billion.Levels of Fe NO higher than 35 parts per billion would be consistent with active eosinophilic inflammation, though atopic individuals generally tend to have higher Fe NO levels.A positive result in the methacholine challenge is defined as the dose of methacholine that causes a decrease in forced expiratory volume in 1 second (FEV Aridol (mannitol inhalation powder; Pharmaxis Ltd, Frenchs Forest, Australia) is now available as a bronchial challenge test kit for the assessment of bronchial hyperresponsiveness.This indirect test offers the advantages of office administration, ease of use, and lower cost than the methacholine challenge.We're searching for answers to some of childhood's diseases, conditions and issues.In addition to our four research focus areas (Aboriginal Health, Brain and Behaviour, Chronic and Severe Diseases, Early Environment), you can also discover more about specific research we're involved in and the technology we use.The use of a LABA, combined with an ICS, is a mainstay of treatment for patients with moderate to severe asthma.Long-acting β-agonists should be used only in combination with ICSs, as indicated by the FDA “black box” warning pointing out that using LABAs alone carries the increased risks of worsening asthma and asthma-related deaths.Meet the entire research team and learn more about the research we fund.See some of the current research projects we are funding: The American Lung Association Airways Clinical Research Centers (ACRC) Network is the nation's largest not-for-profit network of clinical research centers dedicated to asthma and chronic obstructive pulmonary disease (COPD) treatment research, attracting some of the best investigators nationwide.