Prostate Essay Thesis

Serum prostate-specific antigen (PSA) level is generally used as a screening test for asymptomatic patients.Patients with elevated serum PSA level and/or abnormal digital rectal examination undergo Transrectal ultrasound (TRUS) guided biopsy to detect early prostatic carcinoma.Prostate cancer beleive it or not was actually first considered a rare disease,most likely because back then there was shorter life expectancy and poorer detection methods.. In 2010 , 256,000 deaths were resulted because of prostate cancer....

Serum prostate-specific antigen (PSA) level is generally used as a screening test for asymptomatic patients.Patients with elevated serum PSA level and/or abnormal digital rectal examination undergo Transrectal ultrasound (TRUS) guided biopsy to detect early prostatic carcinoma.

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Similar trends are found worldwide to mirror those of the United States.1 However, the progression of prostate cancer is typically slow and does not metastasize all that often.2 Due to this, treatments can typically be life saving and prostate cancer deaths have declined ~35% from 1997 to 2007....

[tags: Cancer, Prostate cancer, Screening] - Introduction: Prostate cancer is the most common cancer in New Zealand and third most common cause of cancer death in the male population (1).

[tags: Cancer, Metastasis, Prostate cancer] - According to the National Cancer Institute, prostate cancer is the second leading cause of mortality from cancer in men.

SEER statistics show that 14% of men will be diagnosed with prostate cancer during their life.

The prostate is a walnut-sized gland of the males’ reproductive system, lying just behind the urinary bladder and in front of the rectum.

Moreover, the prostate is comprised of several types of cells that can become cancerous, but nearly all prostate cancer develops within the glandular tissue that creates the fluid that is added to semen....

For localized prostate cancer, the main treatment is hormone therapy in combination with radiation or surgery but eventually resistance occurs and castration resistant prostate cancer develops (CRPC) [18].

CRPC survives on very low levels of androgen and is often metastatic.

[tags: Cancer, Prostate cancer] - Innovation Statement: We propose to employ an innovative approach to understand the genetic complexity of prostate cancer (PCa) in general and understand the racial disparity between African American (AA) and European American (EA) prostate cancer (PCa) based on screening of driver molecular aberrations on whole-mount radical prostatectomy tissues by considering all tumor foci as detailed below: Study Concept: We developed and implemented an innovative approach to address an important area of PCa research question on in situ evaluation of tumor molecular heterogeneity which has not been considered for in-depth investigation for long time....

[tags: Cancer, Prostate cancer, Metastasis] - Introduction Prostate Cancer (PCa) is the most common cancer affecting men and the second leading cause of cancer death among American men (Qaseem, Denberg, Owens, & Shekelle, 2013).